Throughout biopharmaceutical manufacturing non-conformances, product loss and quality is impacted through unforeseen issues. Applying analytics in real-time has revolutionized the way in which Janssen approach and prevent unwanted deviations in manufacturing.
Projects at the Leiden and Cork large molecule sites align with Manufacturing For the Future (MFF) to deliver customer value and enable business growth and profitability. The PI System and SIMCA-online are cornerstones of this program providing infrastructure and a real-time view of process execution. Open loop optimization suggests set-points for manipulated variables during operation to meet objectives such as maximizing yield, steady production rate, or optimizing CQA’s.
The talk will highlight how the capability to process live data is now a requisite for successful realization of Industrial Internet of Things (IoT) in pursuit of improved industrial performance, with benefits in efficiency, lesser costs and reduced risk.